Bioinformatic Resistome Profiling of Metal Tolerance Mechanisms in Endodontic Infections: Implications for Antimicrobial Nanoparticle-Based Biomaterials

Carlos Alberto Luna-Lara, Carlos Roberto Luna-Dominguez, Rogelio Oliver-Parra, Omaika Victoria Criollo-Barrios, María de los Dolores Vaca-Jasso, Marco Felipe Salas-Orozco · 2026

Read Bioinformatic Resistome Profiling of Metal Tolerance Mechanisms in Endodontic Infections: Implications for Antimicrobial Nanoparticle-Based Biomaterials by Carlos Alberto Luna-Lara, Carlos Roberto Luna-Dominguez, Rogelio Oliver-Parra, Omaika Victoria Criollo-Barrios, María de los Dolores Vaca-Jasso, Marco Felipe Salas-Orozco (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13207848.txt.

Description

Carlos Alberto Luna-Lara and five co-authors map germ defenses against metals in root canal infections, in a study dated 2026. Silver and copper particles are being tested as germ killers for dental materials. Yet many bacteria carry genes that pump metals out or shield the cell, which could blunt those tools.

Working only with public genome data, the team checked bacteria tied to four kinds of tooth-root infection. They searched each genome for seven known metal defense proteins, including pumps for copper and silver. The survey shows how common each defense is across the species involved. Dentists designing particle-based materials can use the map to pick metals that local germs are less equipped to resist.

Catalog record

CREATORCarlos Alberto Luna-Lara, Carlos Roberto Luna-Dominguez, Rogelio Oliver-Parra, Omaika Victoria Criollo-Barrios, María de los Dolores Vaca-Jasso, Marco Felipe Salas-Orozco
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13207848

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