Assessing the degree of cortical dislamination through electrical pattern analysis

Ana Aquiles, Laura Pinedo, Mirelta Regalado, Hiram Luna-Munguia, Fernando Peña-Ortega, Luis Concha, Román Rossi-Pool · 2026

Read Assessing the degree of cortical dislamination through electrical pattern analysis by Ana Aquiles, Laura Pinedo, Mirelta Regalado, Hiram Luna-Munguia, Fernando Peña-Ortega, Luis Concha, Román Rossi-Pool (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13207625.txt.

Description

Ana Aquiles and co-authors present a 2026 study of brain cortex malformation, a leading cause of drug resistant epilepsy in children. They use a rat model where a chemical causes graded cortical damage. Electrode arrays record brain activity at rest and after a stimulus.

A new measure captures how unevenly signals are organised across space. That unevenness tracked the extent and spread of the malformation. It also tied to the balance between excitation and braking in the tissue. The work helps test whether disorganisation itself drives odd activity, a point past work left open. The tools may one day aid surgical planning for children with this condition.

Catalog record

CREATORAna Aquiles, Laura Pinedo, Mirelta Regalado, Hiram Luna-Munguia, Fernando Peña-Ortega, Luis Concha, Román Rossi-Pool
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE66 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13207625

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