Application of the New IMWG/IMS High-Risk Classification for Multiple Myeloma: Analysis of a Large Real-World Romanian Cohort

Sorina Nicoleta Badelita, Sinziana Barbu, Onda-Tabita Calugaru, Cerasela Jardan, Codruta Delia Popa, Larisa Zidaru, Mihai Emanuel Himcinschi, Bogdan Nicolas Smadu, Iulia Ursuleac, Daniel Coriu · 2026

Read Application of the New IMWG/IMS High-Risk Classification for Multiple Myeloma: Analysis of a Large Real-World Romanian Cohort by Sorina Nicoleta Badelita, Sinziana Barbu, Onda-Tabita Calugaru, Cerasela Jardan, Codruta Delia Popa, Larisa Zidaru, Mihai Emanuel Himcinschi, Bogdan Nicolas Smadu, Iulia Ursuleac, Daniel Coriu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13207379.txt.

Description

Sorina Nicoleta Badelita and nine co-authors test a new risk scheme for multiple myeloma in Romania in 2026. Myeloma is a blood cancer of plasma cells with wide variation between patients. New international rules sharpen the high-risk label using gene faults, including damage to a key guard gene and chromosome one changes.

The team rechecked 738 patients diagnosed from 2017 to 2025, with gene test data for 408. A quarter of those were relabeled high-risk under the new rules. Their median survival ran about fifty-two months against sixty-eight for standard risk. Time without disease growth also split clearly, backing the scheme in real-world care.

Catalog record

CREATORSorina Nicoleta Badelita, Sinziana Barbu, Onda-Tabita Calugaru, Cerasela Jardan, Codruta Delia Popa, Larisa Zidaru, Mihai Emanuel Himcinschi, Bogdan Nicolas Smadu, Iulia Ursuleac, Daniel Coriu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13207379

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