Insulin and Incretin Receptor Agonists Reciprocally Alter Their Blood–Brain Barrier Permeabilities

Angeline Fry, Alexis Rose, Riley Weaver, Kim Hansen, James E. Blevins, William A. Banks, Elizabeth M. Rhea · 2026

Read Insulin and Incretin Receptor Agonists Reciprocally Alter Their Blood–Brain Barrier Permeabilities by Angeline Fry, Alexis Rose, Riley Weaver, Kim Hansen, James E. Blevins, William A. Banks, Elizabeth M. Rhea (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13207238.txt.

Description

Fry and six colleagues study how two kinds of drugs affect each other at the blood brain barrier in twenty twenty-six. The barrier is a tight wall that controls what passes from blood into the brain. One drug type is insulin, and the other mimics a gut hormone used for weight and blood sugar care.

The team gave the drugs to lean mice and tracked how fast each one crossed into the brain. A dose of insulin raised how much of the gut hormone drug entered the brain. Two weeks of the gut hormone drug then cut how much insulin crossed in female mice. The results show the barrier shifts with drug use and with sex.

Catalog record

CREATORAngeline Fry, Alexis Rose, Riley Weaver, Kim Hansen, James E. Blevins, William A. Banks, Elizabeth M. Rhea
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13207238

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