Immune Checkpoint-Based Therapies in Colorectal Cancer—Current Approaches and Future Perspectives
Katarzyna Nakielska, Jacek Plewka, Marzena Lenart · 2026
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Description
Katarzyna Nakielska, Jacek Plewka, and Marzena Lenart wrote a 2026 review of immune checkpoint treatments for colorectal cancer. This cancer ranks third in new cases and second in cancer deaths worldwide. Tumours survive partly by switching off immune cells through checkpoint pathways, and drugs that block those switches have changed care for some cancers.
In bowel cancer, though, the benefit stays limited to a small share of patients. The review covers approved checkpoint drugs, trials now running, and fresh targets in this disease. It gives special weight to small-molecule blockers, which could one day replace bulky antibody drugs. The authors close with the directions most likely to widen who benefits.
Catalog record
| CREATOR | Katarzyna Nakielska, Jacek Plewka, Marzena Lenart |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 61 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |