Accuracy and Agreement of a 45 mg Versus a 75 mg 13C-Urea Breath Test for the Diagnosis of Helicobacter pylori Infection in Adults: A Randomized Crossover Trial
Jun Huang, Yaohong Xie, Jian Huang, Bingyun Lu, Ye Chen · 2026
Read Accuracy and Agreement of a 45 mg Versus a 75 mg 13C-Urea Breath Test for the Diagnosis of Helicobacter pylori Infection in Adults: A Randomized Crossover Trial by Jun Huang, Yaohong Xie, Jian Huang, Bingyun Lu, Ye Chen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13205361.txt.
Description
Jun Huang and four co-authors published a randomized crossover trial in twenty twenty-six on whether a smaller dose works for the urea breath test that detects Helicobacter pylori. The stomach bacterium drives ulcers and cancer risk, and breath testing is the gentle way to find it. Four hundred thirty-one adults took both the standard and low-dose tests on the same day.
Agreement between the forty-five and seventy-five milligram versions was substantial, above ninety percent at thirty minutes. Sampling at thirty minutes beat fifteen minutes for both doses. The low dose's accuracy was statistically non-inferior to the standard. Younger and leaner participants did especially well on it. A cheaper, lighter test looks viable for routine diagnosis.
Catalog record
| CREATOR | Jun Huang, Yaohong Xie, Jian Huang, Bingyun Lu, Ye Chen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |