Pericytes: Biomarkers and Roles in Thoracic Aortic Aneurysm
Theodora M. Stougiannou, Dimos Karangelis · 2026
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Description
Theodora Stougiannou and Dimos Karangelis review support cells that wrap tiny blood vessels and their part in bulges of the chest aorta, in work from 2026. These cells, pericytes, sit in the outer layer of the aorta wall, near small feeder vessels and stem cell niches. When the niche goes off balance, a dangerous bulge can form.
In bulged tissue, the support cells change their form and gene pattern. Loss of a growth signal may drive part of that change. The feeder vessels then remodel, which feeds the bulge's growth. The authors weigh recent work on marker genes in these cells. They frame the cells as both warning signs and possible targets for care.
Catalog record
| CREATOR | Theodora M. Stougiannou, Dimos Karangelis |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 65 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |