Smoldering Multiple Myeloma: Early Intervention or Structured Surveillance? A Comprehensive Review of Evidence for and Against Early Therapy

Kirti Arora, Lara Soueid, Louis Williams, Jahanvi Grover, Diana Basali, Jack Khouri, Yuvraj Kaushal, Sandra Mazzoni, Rockey Dahiya, Beth Faiman, Jason Valent, Faiz Anwer, Shahzad Raza · 2026

Read Smoldering Multiple Myeloma: Early Intervention or Structured Surveillance? A Comprehensive Review of Evidence for and Against Early Therapy by Kirti Arora, Lara Soueid, Louis Williams, Jahanvi Grover, Diana Basali, Jack Khouri, Yuvraj Kaushal, Sandra Mazzoni, Rockey Dahiya, Beth Faiman, Jason Valent, Faiz Anwer, Shahzad Raza (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13204926.txt.

Description

Arora and co-authors review a key choice in smoldering multiple myeloma, a quiet blood disorder with no symptoms. Some patients stay stable for years, while others progress to full myeloma. Care has long meant close watch, with treatment held back.

New risk scores and new drugs have revived debate about treating high-risk patients early. The review weighs trial and watch-based study results on survival, time to progression, side effects, and quality of life. It sets out where early therapy may help and where watchful care still seems safer for patients today.

Catalog record

CREATORKirti Arora, Lara Soueid, Louis Williams, Jahanvi Grover, Diana Basali, Jack Khouri, Yuvraj Kaushal, Sandra Mazzoni, Rockey Dahiya, Beth Faiman, Jason Valent, Faiz Anwer, Shahzad Raza
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13204926

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