Phosphorylated Alpha-Synuclein and Carboxymethyllysine in the Epidermis of Type 2 Diabetes Patients: Preliminary Observations
Bernard Kordas, Wojciech Matuszewski, Robert Modzelewski, Judyta Juranek · 2026
Read Phosphorylated Alpha-Synuclein and Carboxymethyllysine in the Epidermis of Type 2 Diabetes Patients: Preliminary Observations by Bernard Kordas, Wojciech Matuszewski, Robert Modzelewski, Judyta Juranek (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13204647.txt.
Description
Bernard Kordas and three co-authors looked for two marker proteins in the skin of people with type 2 diabetes in a 2026 preliminary study. One marker is a modified form of alpha-synuclein, the protein tied to Parkinson's disease, which may also connect to diabetes. The other, carboxymethyllysine, builds up under long-term sugar stress and signals tissue damage.
The team took small skin biopsies from seven patients with long-standing diabetes and seven healthy volunteers and stained them for both markers. The sugar-stress marker covered significantly more area in diabetic skin. The synuclein marker's area did not differ, though its signal intensity was higher in patients by a second measure. The authors call for larger follow-up work.
Catalog record
| CREATOR | Bernard Kordas, Wojciech Matuszewski, Robert Modzelewski, Judyta Juranek |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |