Exploring Autologous Dendritic Cells for T Cell Modulation: A Step Towards Personalized Medicine in Leishmaniasis

Mafalda Meunier, Ana Valério-Bolas, Armanda Rodrigues, Flávia Fróis-Martins, Rui Ferreira, Inês Cardoso, Marta Monteiro, Joana Palma-Marques, Manuela Carvalheiro, Telmo Nunes, Wilson T. Antunes, Graça Alexandre-Pires, Isabel Pereira da Fonseca, Gabriela Santos-Gomes · 2026

Read Exploring Autologous Dendritic Cells for T Cell Modulation: A Step Towards Personalized Medicine in Leishmaniasis by Mafalda Meunier, Ana Valério-Bolas, Armanda Rodrigues, Flávia Fróis-Martins, Rui Ferreira, Inês Cardoso, Marta Monteiro, Joana Palma-Marques, Manuela Carvalheiro, Telmo Nunes, Wilson T. Antunes, Graça Alexandre-Pires, Isabel Pereira da Fonseca, Gabriela Santos-Gomes (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13204335.txt.

Description

Mafalda Meunier leads a team of fourteen in a 2026 study on steering immune cells against leishmaniasis, a parasite disease spread by sand flies. Dendritic cells spark the T cell arm of immunity, so they are a natural lever for tailored care. The team primed these cells with tiny parcels shed by the parasite.

In lab dishes, the primed cells switched on sensing genes and showed more of the surface flags that present targets to T cells. T cells grown with them shifted their mix in response. The authors frame the work as a step toward patient-matched immune therapy for this disease.

Catalog record

CREATORMafalda Meunier, Ana Valério-Bolas, Armanda Rodrigues, Flávia Fróis-Martins, Rui Ferreira, Inês Cardoso, Marta Monteiro, Joana Palma-Marques, Manuela Carvalheiro, Telmo Nunes, Wilson T. Antunes, Graça Alexandre-Pires, Isabel Pereira da Fonseca, Gabriela Santos-Gomes
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE62 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13204335

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