Resolvin D1 in the Lipopolysaccharide-Induced Inflammatory Microenvironment Mediates Resolution in Human Monocytic THP-1 Cells
Zhe Xing, Qian Zhao, Xiaoli He, Jiazheng Cai, Yaxin Xue, Christopher Graham Fenton, Alpdogan Kantarci, Kristin Andreassen Fenton, Xiaoli An, Ying Xue · 2026
Read Resolvin D1 in the Lipopolysaccharide-Induced Inflammatory Microenvironment Mediates Resolution in Human Monocytic THP-1 Cells by Zhe Xing, Qian Zhao, Xiaoli He, Jiazheng Cai, Yaxin Xue, Christopher Graham Fenton, Alpdogan Kantarci, Kristin Andreassen Fenton, Xiaoli An, Ying Xue (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13204318.txt.
Description
Ten authors present a study dated two thousand twenty-six on a molecule that helps switch inflammation off. Resolvin D1 is made by the body to resolve inflammation rather than merely block it. The team tested it on human monocytes, immune cells provoked by a bacterial toxin.
Cells were treated with the toxin, the resolvin, or a control for a day. The resolvin lowered two inflammatory signals the toxin raised. Gene-readout scans found wide expression changes, and the resolvin boosted genes tied to antioxidant defense and cell survival. Two classic inflammatory pathways were checked to pin down the mechanism.
Catalog record
| CREATOR | Zhe Xing, Qian Zhao, Xiaoli He, Jiazheng Cai, Yaxin Xue, Christopher Graham Fenton, Alpdogan Kantarci, Kristin Andreassen Fenton, Xiaoli An, Ying Xue |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |