Constrained Spherical Deconvolution White Matter Tractography in Neuro-Oncology and Deep Brain Stimulation: An Illustrative Case Series

Francesca Romana Barbieri, Massimo Marano, Daniele Marruzzo, Alessandra Ricci, Brunetto De Sanctis, Alessandro Riario Sforza, Riccardo Paracino, Stefano Toro, Serena Pagano, Fabrizio Mancini, Carolina Noya, Davide Luglietto, Riccardo Antonio Ricciuti · 2026

Read Constrained Spherical Deconvolution White Matter Tractography in Neuro-Oncology and Deep Brain Stimulation: An Illustrative Case Series by Francesca Romana Barbieri, Massimo Marano, Daniele Marruzzo, Alessandra Ricci, Brunetto De Sanctis, Alessandro Riario Sforza, Riccardo Paracino, Stefano Toro, Serena Pagano, Fabrizio Mancini, Carolina Noya, Davide Luglietto, Riccardo Antonio Ricciuti (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13204242.txt.

Description

Francesca Romana Barbieri and co-authors show, through twenty cases of brain surgery, how a newer diffusion MRI method maps the white matter paths in the brain before an operation. Sparing those paths is key in tumor surgery and in deep brain stimulation. The older tensor method blurs fibers that cross; constrained spherical deconvolution picks them apart.

Fifteen people with tumors and five with functional disorders, treated between 2022 and 2024, had their key paths rebuilt from scans taken before surgery. The maps fed the plans for each case and guided the work as it went on. The series shows where the sharper images changed plans or made the teams more sure of their course. Better maps of these paths are, in effect, a safety tool in the operating room.

Catalog record

CREATORFrancesca Romana Barbieri, Massimo Marano, Daniele Marruzzo, Alessandra Ricci, Brunetto De Sanctis, Alessandro Riario Sforza, Riccardo Paracino, Stefano Toro, Serena Pagano, Fabrizio Mancini, Carolina Noya, Davide Luglietto, Riccardo Antonio Ricciuti
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13204242

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