New Perspectives and Open Issues in the Adjuvant and Neoadjuvant Treatment of Melanoma
Andrea Spagnoletti, Lorenza Di Guardo, Alice Indini, Massimo Di Nicola, Roberto Patuzzo, Andrea Maurichi, Paolo Fava, Gabriele Roccuzzo, Alessandro Minisini, Federico Pravisano, Jacopo Pigozzo, Luisa Piccin, Carolina Cimminiello, Nikolaos Papadopoulos, Michele Del Vecchio · 2026
Read New Perspectives and Open Issues in the Adjuvant and Neoadjuvant Treatment of Melanoma by Andrea Spagnoletti, Lorenza Di Guardo, Alice Indini, Massimo Di Nicola, Roberto Patuzzo, Andrea Maurichi, Paolo Fava, Gabriele Roccuzzo, Alessandro Minisini, Federico Pravisano, Jacopo Pigozzo, Luisa Piccin, Carolina Cimminiello, Nikolaos Papadopoulos, Michele Del Vecchio (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13204206.txt.
Description
Andrea Spagnoletti and co-authors review, in 2026, open questions in drug treatment given around surgery for melanoma, a serious skin cancer. Treatment before or after surgery has cut the return of high-risk disease and spread to distant sites. Gains have reached earlier stages too, yet many choices remain unsettled.
Open issues include how to treat the earliest high-risk stage and what to do when disease returns during treatment. The review covers immune drug pairs, personal vaccines made from tumor markers, and tests that may refine risk estimates. Stage alone still leads to over- and under-treatment, the authors warn. Better risk tools are the path forward.
Catalog record
| CREATOR | Andrea Spagnoletti, Lorenza Di Guardo, Alice Indini, Massimo Di Nicola, Roberto Patuzzo, Andrea Maurichi, Paolo Fava, Gabriele Roccuzzo, Alessandro Minisini, Federico Pravisano, Jacopo Pigozzo, Luisa Piccin, Carolina Cimminiello, Nikolaos Papadopoulos, Michele Del Vecchio |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |