Single-Nucleotide Polymorphism (SNP) c.73G>A in the UBC9 (E2) SUMO Gene and Breast Cancer Risk in Polish Women
Hanna Romanowicz, Grzegorz Sychowski, Szymon Kalinowski, Szymon Sypniewski, Oleksandr Zakharin, Marek Zadrożny, Honorata Łukasiewicz, Dariusz Samulak, Beata Smolarz · 2026
Read Single-Nucleotide Polymorphism (SNP) c.73G>A in the UBC9 (E2) SUMO Gene and Breast Cancer Risk in Polish Women by Hanna Romanowicz, Grzegorz Sychowski, Szymon Kalinowski, Szymon Sypniewski, Oleksandr Zakharin, Marek Zadrożny, Honorata Łukasiewicz, Dariusz Samulak, Beata Smolarz (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13204008.txt.
Description
Hanna Romanowicz and eight co-authors published a 2026 study of a single-letter gene variant and breast cancer risk in Polish women. The gene, UBC9, runs a tagging system that affects DNA repair and is often overproduced in breast tumors. The team genotyped tumor tissue from 100 women with ductal breast cancer and compared it with samples from 100 cancer-free women.
The mixed genotype and the variant allele both appeared more often in the cancer group, marking higher risk. The mixed genotype also clustered in stage II tumors, hinting at a link with invasiveness. No ties showed to tumor stage scales, grade, or hormone status. The authors call the variant a possible risk marker, while stressing that larger studies must confirm it.
Catalog record
| CREATOR | Hanna Romanowicz, Grzegorz Sychowski, Szymon Kalinowski, Szymon Sypniewski, Oleksandr Zakharin, Marek Zadrożny, Honorata Łukasiewicz, Dariusz Samulak, Beata Smolarz |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |