Comparison of the Sedative and Cardiovascular Effects of Azaperone and Acepromazine in Dogs

Marco Antonio de Paz-Campos, Lilia Gutiérrez-Olvera, Héctor Salvador Sumano-López, Graciela Tapia-Pérez, José Antonio Ibancovichi-Camarillo, Uriel López-Parrilla, Williams Alexis Bernal-Palapa, Regina Paola Hernández-Guzmán, Julio Raúl Chávez-Monteagudo · 2026

Read Comparison of the Sedative and Cardiovascular Effects of Azaperone and Acepromazine in Dogs by Marco Antonio de Paz-Campos, Lilia Gutiérrez-Olvera, Héctor Salvador Sumano-López, Graciela Tapia-Pérez, José Antonio Ibancovichi-Camarillo, Uriel López-Parrilla, Williams Alexis Bernal-Palapa, Regina Paola Hernández-Guzmán, Julio Raúl Chávez-Monteagudo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13203426.txt.

Description

Marco Antonio de Paz-Campos and co-authors compared two calming drugs in dogs, checking both sedation depth and heart effects, in a 2026 study. Vets need dogs calm for exams and minor procedures, but many sedatives slow the heart or drop blood pressure. Twenty-four dogs received azaperone or acepromazine, and the team scored posture, eyelid reflex, eye position, and response on a standard sedation scale. A cuff method tracked pressures and heart rate over time.

Time changed every measure, as expected as the drugs took hold and faded. Heart rate did not differ by drug. Azaperone gave moderate sedation about twenty minutes after dosing. It caused neither a slow heart nor a worrying fall in blood pressure. The authors present it as a steady option when heart safety matters in dog sedation.

Catalog record

CREATORMarco Antonio de Paz-Campos, Lilia Gutiérrez-Olvera, Héctor Salvador Sumano-López, Graciela Tapia-Pérez, José Antonio Ibancovichi-Camarillo, Uriel López-Parrilla, Williams Alexis Bernal-Palapa, Regina Paola Hernández-Guzmán, Julio Raúl Chávez-Monteagudo
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE18 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13203426

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