Genomic epidemiological patterns and antifungal resistance profiles of Candidozyma auris in China: Spatiotemporal dynamics and persistent colonization

Junmin Cao, Xiang-Yu Wang, Cong Qin, Danxia Gu, Rong Zhang, Hongwei Zhou, Ruichao Li · 2026

Read Genomic epidemiological patterns and antifungal resistance profiles of Candidozyma auris in China: Spatiotemporal dynamics and persistent colonization by Junmin Cao, Xiang-Yu Wang, Cong Qin, Danxia Gu, Rong Zhang, Hongwei Zhou, Ruichao Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13203038.txt.

Description

A drug-resistant yeast is spreading through hospitals, and a 2026 genomic study led by Junmin Cao tracks its patterns across China. The research article studies twenty-two ICU patients colonized or infected with Candidozyma auris, sequencing twenty-five isolates and testing their antifungal susceptibility.

Every isolate was immune to fluconazole, and most were immune to amphotericin B too, while the echinocandin drug class remained effective in testing. The gene reads split into two global clades with distinct resistance-gene variants, though single mutations did not predict drug response neatly. Matching 210 genomes traced arrivals from Canada, South Korea, and Pakistan, with Beijing and Guangdong as domestic spread hubs.

Catalog record

CREATORJunmin Cao, Xiang-Yu Wang, Cong Qin, Danxia Gu, Rong Zhang, Hongwei Zhou, Ruichao Li
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE31 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13203038

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