Bio-inspired self-assembly of omega-3 fatty acids and peptides for responsive drug delivery

Simone Braccia, Luigi Alfano, Maria Carmen Ragosta, Rosa Bellavita, Gabriella D'Auria, Emanuela Esposito, Federica Donadio, Sara Palladino, Alessandro di Vaio, Rosa Camerlingo, Lucia Falcigno, Annarita Falanga, Michelino de Laurentiis, Antonio Giordano, Stefania Galdiero · 2026

Read Bio-inspired self-assembly of omega-3 fatty acids and peptides for responsive drug delivery by Simone Braccia, Luigi Alfano, Maria Carmen Ragosta, Rosa Bellavita, Gabriella D'Auria, Emanuela Esposito, Federica Donadio, Sara Palladino, Alessandro di Vaio, Rosa Camerlingo, Lucia Falcigno, Annarita Falanga, Michelino de Laurentiis, Antonio Giordano, Stefania Galdiero (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13202583.txt.

Description

Simone Braccia and a large team build a self-assembling drug carrier in a 2026 paper. Omega-3 fatty acids pair with peptides to form the delivery particles. Cancer drugs ride inside until a tumor enzyme gives the signal.

Two well-known drugs, doxorubicin and pemetrexed, were loaded in tests. A protein-cutting linker responds to an enzyme common in tumors. Release then happens on demand, near the cancer cells themselves. The design aims to cut whole-body toxicity of chemotherapy. Personalized treatment is the longer goal of the platform. Readers see food chemistry turned into a smart medicine capsule.

Catalog record

CREATORSimone Braccia, Luigi Alfano, Maria Carmen Ragosta, Rosa Bellavita, Gabriella D'Auria, Emanuela Esposito, Federica Donadio, Sara Palladino, Alessandro di Vaio, Rosa Camerlingo, Lucia Falcigno, Annarita Falanga, Michelino de Laurentiis, Antonio Giordano, Stefania Galdiero
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE77 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13202583

Browse the full library · About the Tower of Babel