Cardiac magnetic resonance-derived left atrioventricular coupling index predicts outcome in reduced ejection fraction

Marco Guglielmo, Damiano Fedele, Luca Bergamaschi, Matteo Armillotta, Francesco Angeli, Mariachiara Ciarlantini, Ilaria Buccella, Carmine Pizzi, Theo Pezel, Giovanni Donato Aquaro, Andrea Baggiano, Andrea Barison, Jan Bogaert, Leonardo Calò, Giovanni Camastra, Samuela Carigi, Nazario Carrabba, Grazi · 2026

Read Cardiac magnetic resonance-derived left atrioventricular coupling index predicts outcome in reduced ejection fraction by Marco Guglielmo, Damiano Fedele, Luca Bergamaschi, Matteo Armillotta, Francesco Angeli, Mariachiara Ciarlantini, Ilaria Buccella, Carmine Pizzi, Theo Pezel, Giovanni Donato Aquaro, Andrea Baggiano, Andrea Barison, Jan Bogaert, Leonardo Calò, Giovanni Camastra, Samuela Carigi, Nazario Carrabba, Grazi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13202458.txt.

Description

Marco Guglielmo and co-authors test a coupling measure between the heart's upper and lower left chambers as a predictor in weak-heart patients in a 2026 study. The index divides left atrial by left ventricular volume at filling, both read from cardiac MRI. Patients came from a multicenter registry of people with ejection fraction under fifty percent.

Statistical models weighed the index against death, and against death or heart-failure events, with competing-risk methods for heart failure alone. Time-based accuracy analysis set cutoffs for three-year outcomes. The premise is that a stiff, overfilled atrium coupled to a failing ventricle marks advanced disease better than either chamber alone. The authors report the index carries prognostic value in this reduced-function population, adding a simple ratio to the MRI report.

Catalog record

CREATORMarco Guglielmo, Damiano Fedele, Luca Bergamaschi, Matteo Armillotta, Francesco Angeli, Mariachiara Ciarlantini, Ilaria Buccella, Carmine Pizzi, Theo Pezel, Giovanni Donato Aquaro, Andrea Baggiano, Andrea Barison, Jan Bogaert, Leonardo Calò, Giovanni Camastra, Samuela Carigi, Nazario Carrabba, Grazi
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE49 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13202458

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