Topical therapies for diabetic foot ulcers: a systematic review and network meta-analysis
Lihong Chen, Jui-Ching Chen, Ting Lin, Feiyan Shi, Dawei Chen, Chun Wang, Yun Gao, Harikrishna K Ragavan Nair, Xingwu Ran · 2026
Read Topical therapies for diabetic foot ulcers: a systematic review and network meta-analysis by Lihong Chen, Jui-Ching Chen, Ting Lin, Feiyan Shi, Dawei Chen, Chun Wang, Yun Gao, Harikrishna K Ragavan Nair, Xingwu Ran (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13202107.txt.
Description
Creams, gels, and biological dressings compete to heal diabetic foot ulcers, and a 2026 systematic review headed by Lihong Chen ranks them against each other. The review and network meta-analysis gathers randomized trials of topical therapies, a treatment area where direct head-to-head comparisons are scarce.
Searching three databases through early 2025, the authors included fifty-one trials with 6,161 patients and twenty-three different interventions. Twelve topical therapies improved healing rates over standard care, and placenta-derived products showed the largest benefit while also reducing adverse events in the analysis. Evidence quality was mostly low to moderate, so the authors urge better trials before firm treatment rankings.
Catalog record
| CREATOR | Lihong Chen, Jui-Ching Chen, Ting Lin, Feiyan Shi, Dawei Chen, Chun Wang, Yun Gao, Harikrishna K Ragavan Nair, Xingwu Ran |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |