Symptom severity, neighborhood crime, and neural correlates of reappraisal in patients with major depression and social anxiety
Cope Feurer, Jagan Jimmy, Melissa Uribe, Katie L Burkhouse, Stewart A Shankman, K Luan Phan, Olusola Ajilore, Heide Klumpp · 2026
Read Symptom severity, neighborhood crime, and neural correlates of reappraisal in patients with major depression and social anxiety by Cope Feurer, Jagan Jimmy, Melissa Uribe, Katie L Burkhouse, Stewart A Shankman, K Luan Phan, Olusola Ajilore, Heide Klumpp (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13200157.txt.
Description
Cope Feurer and co-authors study how neighborhood adversity shapes brain responses during emotion control in depression and social anxiety in a 2026 paper. Reappraisal, rethinking a negative scene to soften its impact, is often weaker in these disorders, with less frontal brain activation. Yet findings on severity links have been uneven across studies, which hints at a missing moderator.
The team reasoned that reappraisal may help mainly under uncontrollable adversity. Patients with major depression or social anxiety did a reappraisal task in a scanner, and their home addresses were coded for neighborhood disadvantage and crime. The study tests whether those neighborhood factors change the link between symptom severity and brain activation.
Catalog record
| CREATOR | Cope Feurer, Jagan Jimmy, Melissa Uribe, Katie L Burkhouse, Stewart A Shankman, K Luan Phan, Olusola Ajilore, Heide Klumpp |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |