Successive waves of transcriptional repression and de-repression license cell cycle progression in an archaeon
Yunfeng Yang, Shikuan Liang, Zixin Geng, Miguel V Gomez-Raya-Vilanova, Wenying Xia, Junfeng Liu, Qihong Huang, Jinfeng Ni, Qunxin She, Mart Krupovic, Yulong Shen · 2026
Read Successive waves of transcriptional repression and de-repression license cell cycle progression in an archaeon by Yunfeng Yang, Shikuan Liang, Zixin Geng, Miguel V Gomez-Raya-Vilanova, Wenying Xia, Junfeng Liu, Qihong Huang, Jinfeng Ni, Qunxin She, Mart Krupovic, Yulong Shen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13199686.txt.
Description
Yunfeng Yang and co-authors present a 2026 study of the cell cycle in a heat-loving archaeon. The microbe runs an ordered cycle much like that of complex cells, but its control logic was unclear. The team found three brake proteins that hold key cycle genes off, each rising at a set phase.
One brake is freed by a tag from a clock-like enzyme just before the split phase. The brakes grip shared DNA marks with unlike strength, so waves of release time the phases. The team frames it as a simple brake-point system, a step toward complex cell control.
Catalog record
| CREATOR | Yunfeng Yang, Shikuan Liang, Zixin Geng, Miguel V Gomez-Raya-Vilanova, Wenying Xia, Junfeng Liu, Qihong Huang, Jinfeng Ni, Qunxin She, Mart Krupovic, Yulong Shen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |