HAK-actin, a U-ExM-compatible probe to image the actin cytoskeleton

Olivier Mercey, Luc Reymond, Florent Lemaître, Isabelle Mean, Marine H Laporte, Marine Olivetta, Karin Sadoul, Omaya Dudin, Virginie Hamel, Paul Guichard · 2026

Read HAK-actin, a U-ExM-compatible probe to image the actin cytoskeleton by Olivier Mercey, Luc Reymond, Florent Lemaître, Isabelle Mean, Marine H Laporte, Marine Olivetta, Karin Sadoul, Omaya Dudin, Virginie Hamel, Paul Guichard (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13198096.txt.

Description

Olivier Mercey and nine co-authors present a new probe that makes the actin web inside cells easy to see under a swelling microscope trick. That trick blows samples up for sharp views, and it works well for one cell web but poorly for actin, the web that shapes and moves cells.

Their built probe stains actin in a strong, even way across many sample kinds. Human cells, small microbes, and mouse eye tissue all lit up well. The tool is simple and repeats well across labs. It fills a clear gap for cell shape studies at fine scale.

Catalog record

CREATOROlivier Mercey, Luc Reymond, Florent Lemaître, Isabelle Mean, Marine H Laporte, Marine Olivetta, Karin Sadoul, Omaya Dudin, Virginie Hamel, Paul Guichard
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE68 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13198096

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