Glucagon-Like Peptide-1 Receptor Agonists in Hip and Knee Arthroplasty: A Comprehensive Systematic Review and Meta-Analysis of Perioperative and Postoperative Outcomes
Benjamin Wajda, Darren Van Essen, Sabrina Martini, Golpira Elmi Assadzadeh, Rajrishi Sharma, Jason Werle · 2026
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Description
Benjamin Wajda and co-authors review weight loss drugs of the GLP-1 class around hip and knee replacement surgery in a 2026 analysis. Obesity raises demand for joint replacement and lifts the risk of infection, wound problems, and repeat surgery. Use of these drugs before surgery is growing, but safety was unclear.
The review pooled thirteen record based studies with a very large patient count. Drug use was linked to lower odds of joint infection in the first ninety days. The authors also gathered data on other complications and care use at ninety days and at one to two years, to weigh benefit against risk.
Catalog record
| CREATOR | Benjamin Wajda, Darren Van Essen, Sabrina Martini, Golpira Elmi Assadzadeh, Rajrishi Sharma, Jason Werle |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |