Four-Limb Coordinated Training and Neuroplasticity in Older Adults with Cognitive Frailty: Mechanisms and Clinical Evidence
Wenbiao Guan, ChaoHui Li, Tiansheng Bu · 2026
Read Four-Limb Coordinated Training and Neuroplasticity in Older Adults with Cognitive Frailty: Mechanisms and Clinical Evidence by Wenbiao Guan, ChaoHui Li, Tiansheng Bu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13197674.txt.
Description
Wenbiao Guan and co-authors review exercise that moves all four limbs together for older adults with cognitive frailty, in this 2026 paper. The syndrome pairs body frailty with thinking problems short of dementia. It raises the risk of disability and death, yet exercise advice for it is vague.
Following standard review guidance, the team gathered six controlled studies from one database. Programs included a Chinese exercise form, virtual reality training, active games, and resistance work. Results generally favored the training for thinking, frailty, walking, and balance. Direct brain evidence was thin, though blood flow hints appeared. The authors call for sharper trials with brain measures built in.
Catalog record
| CREATOR | Wenbiao Guan, ChaoHui Li, Tiansheng Bu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 53 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |