Influence of reward-related genetic variants on BMI and predisposition to obesity: Systematic review and meta-analysis
Bernardo Perin Cima, Mariana Meira Scudeler, Juliana Dal-Ri Lindenau, Yara Costa Netto Muniz · 2026
Read Influence of reward-related genetic variants on BMI and predisposition to obesity: Systematic review and meta-analysis by Bernardo Perin Cima, Mariana Meira Scudeler, Juliana Dal-Ri Lindenau, Yara Costa Netto Muniz (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13196784.txt.
Description
Bernardo Perin Cima and colleagues wrote a 2026 review and combined analysis on genes, brain reward, and body weight. The reward system is the brain circuit that drives craving and pleasure from food. The team asked whether gene variants in that circuit link to higher body mass.
They searched five databases and kept 117 studies, with 31 fit for combined math analysis. Eighteen variants showed links to body mass index, a ratio of weight to height. Five variants had the strongest support. One variant in a dopamine gene, a chemical messenger gene, linked clearly to obesity. The findings may guide more personal plans to prevent weight gain.
Catalog record
| CREATOR | Bernardo Perin Cima, Mariana Meira Scudeler, Juliana Dal-Ri Lindenau, Yara Costa Netto Muniz |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |