Non-destructive debridement and tuneable ion release via magnesium abrasion and electro-dissolution promote bone regeneration and osseointegration of infected implants
Zhixiang Nie, Yasheng Sun, Ke Li, Jukka P. Matinlinna, William M. Palin, Liam M. Grover, Zhen Zhang · 2026
Read Non-destructive debridement and tuneable ion release via magnesium abrasion and electro-dissolution promote bone regeneration and osseointegration of infected implants by Zhixiang Nie, Yasheng Sun, Ke Li, Jukka P. Matinlinna, William M. Palin, Liam M. Grover, Zhen Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13196099.txt.
Description
Zhixiang Nie and six co-authors clean infected metal implants with magnesium, of all things, and show the cleaning itself helps bone regrow, in this 2026 study. Implant infections usually force damaging scrubbing or removal. Magnesium is softer than titanium, so its particles can scour biofilm off an implant without scratching it, and the excess can then be dissolved away electrically.
In animals, the treatment steered early inflammation toward healing: neutrophils retired sooner, their web traps thinned, and macrophages switched to a repair mode. Gene activity confirmed inflammatory pathways quieting. New bone formed faster and better organized, and the implants locked in firmly a second time. The authors propose the method as a surface sparing rescue for infected hardware that patients cannot afford to lose.
Catalog record
| CREATOR | Zhixiang Nie, Yasheng Sun, Ke Li, Jukka P. Matinlinna, William M. Palin, Liam M. Grover, Zhen Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 71 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |