Methodological limitations of NOM in the WSES acute appendicitis guidelines
Pedro Henrique Grosso, João Vitor Grosso, Francisco Alcides Dias Filho · 2026
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Description
Grosso, Grosso, and Dias Filho challenge a 2025 surgical guideline that endorses treating simple appendicitis with antibiotics instead of surgery. Writing in 2026, they grade the evidence behind that advice and find it weak. Scans taken at admission, they argue, miss small perforations and cannot rule out hidden tumors of the appendix, found in up to about three percent of cases.
They also cite follow-up data showing that antibiotic-treated patients relapse at a rate above forty percent within three years. The apparent safety of the drug-first route, they say, is skewed by these flaws. Their letter argues that lasting repair and safe surgery should stay the main goals in emergency abdominal care.
Catalog record
| CREATOR | Pedro Henrique Grosso, João Vitor Grosso, Francisco Alcides Dias Filho |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |