UNCP-18 is a C. elegans STXBP homolog that is required for full fertility
Isabella K Jacobs, Nina Peel · 2026
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Description
Isabella K Jacobs and Nina Peel study a worm gene needed for full breeding in a 2026 paper. The gene makes a helper that lets cells fuse small sacs with their outer skin to ship goods out. Its kin in humans help nerve cells send signals, and faults cause nerve disease.
Tagged copies of the helper sit at the skin of many worm cells, as its shipping role would suggest. Worms that lack it have smaller broods, and mating only partly restores the count. More flaws in the germ line point to roles past sperm, and the worm may model non-nerve roles of the kin.
Catalog record
| CREATOR | Isabella K Jacobs, Nina Peel |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 12 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |