Editorial: The role of innate immunity in the pathogenesis of autoimmune and autoinflammatory diseases
Carmelo Carmona-Rivera, Diana Gómez-Martín, José Luis Maravillas-Montero, José Jiram Torres-Ruiz · 2026
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Description
Carmelo Carmona-Rivera and co-authors open a 2026 journal collection on how the innate immune system drives autoimmune disease. Older work stressed the adaptive arm, the part that learns targets over time. The editors argue that this view misses how disease starts and flares.
The collected studies span lab work, gene data, patient studies, and reviews, yet they converge on one claim: innate immune faults sit at the core of many such diseases. Cells like macrophages and neutrophils shift states under cues from metabolism, gene marks, and surroundings. Sample papers link a gene-editing mark to joint inflammation and a hub gene to thyroid attack. Readers get a map of how first-line immune cells spark and sustain self-attack.
Catalog record
| CREATOR | Carmelo Carmona-Rivera, Diana Gómez-Martín, José Luis Maravillas-Montero, José Jiram Torres-Ruiz |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 7 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |