MicroRNA expression profiles in abdominal aortic aneurysms: A systematic review of potential diagnostic and prognostic biomarkers
Pooya Eini, Peyman Eini, Homa serpoush, Mohammad Rezayee, Jason Tremblay · 2026
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Description
Pooya Eini and co-authors review tiny RNA markers for a dangerous aortic swelling in a 2026 paper. An abdominal aortic aneurysm can rupture without warning, and doctors lack a blood test to catch it early. MicroRNAs, small gene regulators shed into blood, are promising candidates.
Thirty-nine studies met the review's bar. A consistent panel emerged: several microRNAs ran high in patients, including miR-21 and miR-155, while others, like the let-7 family, ran low. The changes showed in plasma, serum, and vessel tissue, and the molecules feed into pathways for inflammation and vessel wall breakdown. Reported accuracy varied a lot between studies. The authors call the panel promising for screening, pending standard methods and prospective validation.
Catalog record
| CREATOR | Pooya Eini, Peyman Eini, Homa serpoush, Mohammad Rezayee, Jason Tremblay |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 80 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |