Unravelling mesenteric fibrosis in small intestinal neuroendocrine tumours and implications for clinical management
Maria Castanho Martins, Eva van der Slik, Johannes Hofland, Anela Blažević, Harry Hodgetts, Dalvinder Mandair, Christos Toumpanakis, Martyn E Caplin, Leo J Hofland, Wouter W de Herder, Krista Rombouts, Richard A Feelders · 2026
Read Unravelling mesenteric fibrosis in small intestinal neuroendocrine tumours and implications for clinical management by Maria Castanho Martins, Eva van der Slik, Johannes Hofland, Anela Blažević, Harry Hodgetts, Dalvinder Mandair, Christos Toumpanakis, Martyn E Caplin, Leo J Hofland, Wouter W de Herder, Krista Rombouts, Richard A Feelders (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13192698.txt.
Description
Castanho Martins and co-authors review a scarring reaction that often grows around tumors of the small intestine. These slow tumors can sit quietly for years, but when they spread to the sheet of tissue that holds the gut, dense scar tissue may follow. Their 2026 review sums up what is known about that scarring and where the gaps lie.
The scar tissue can block the gut or starve it of blood, and surgery is now the only real treatment. The authors note that even basic terms and grading scales for the condition are still missing. Early work points to serotonin and growth signals that switch on scar-forming cells near the tumor. They call for shared definitions and joint research to open the way to drug treatments.
Catalog record
| CREATOR | Maria Castanho Martins, Eva van der Slik, Johannes Hofland, Anela Blažević, Harry Hodgetts, Dalvinder Mandair, Christos Toumpanakis, Martyn E Caplin, Leo J Hofland, Wouter W de Herder, Krista Rombouts, Richard A Feelders |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 59 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |