Protective Role of Rosmarinic Acid–Enriched Elsholtzia kachinensis Extract Against Oxidative and Inflammatory Stress in Human Trophoblasts Through the miR‐138‐5p/FOXC1 Pathway

Wittaya Chaiwangyen, Orawan Khantamat, Amnart Onsa-ard, Napapan Kangwan, Wachiraporn Tipsuwan, Angkana Songkrao, Apirak Katasai, Apisit Phngam, Piyawan Nuntaboon, Ramita Sangprachum, Pilaiporn Thippraphan, Francisco Lázaro Pereira de Sousa · 2026

Read Protective Role of Rosmarinic Acid–Enriched Elsholtzia kachinensis Extract Against Oxidative and Inflammatory Stress in Human Trophoblasts Through the miR‐138‐5p/FOXC1 Pathway by Wittaya Chaiwangyen, Orawan Khantamat, Amnart Onsa-ard, Napapan Kangwan, Wachiraporn Tipsuwan, Angkana Songkrao, Apirak Katasai, Apisit Phngam, Piyawan Nuntaboon, Ramita Sangprachum, Pilaiporn Thippraphan, Francisco Lázaro Pereira de Sousa (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13191767.txt.

Description

Wittaya Chaiwangyen and a team of co-authors test a plant extract for shielding placenta cells from stress, in a paper dated twenty twenty-six. The plant, Elsholtzia kachinensis, is rich in rosmarinic acid. One extract fraction showed the strongest antioxidant power and the richest store of plant chemicals. The team treated human trophoblast cells, which form the placenta's outer layer, with a bacterial toxin plus the extract.

The extract saved cell growth, movement, and invasion that the toxin had harmed. It cut cell suicide, oxygen waste, and swelling signals. It worked by lowering a small RNA that the toxin raises and restoring its target gene. The authors see a lead for guarding pregnancy health.

Catalog record

CREATORWittaya Chaiwangyen, Orawan Khantamat, Amnart Onsa-ard, Napapan Kangwan, Wachiraporn Tipsuwan, Angkana Songkrao, Apirak Katasai, Apisit Phngam, Piyawan Nuntaboon, Ramita Sangprachum, Pilaiporn Thippraphan, Francisco Lázaro Pereira de Sousa
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE44 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13191767

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