Burden of Intrapancreatic Fat Deposition in Type 2 Diabetes and the Role of Obesity: A Systematic Review and Meta-Analysis
Hyun Hee Sul, Saeed Ahmad, Pojsakorn Danpanichkul, Alessandro Mantovani, Matheus Souza, Maxim S. Petrov · 2026
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Description
Hyun Hee Sul and co-authors reviewed studies of fat inside the pancreas in people with type 2 diabetes, in work published in 2026. Fat in this organ may play a role in how the disease starts, but the size of the link was unclear. The review pooled thirty studies with close to four thousand people.
People with diabetes had clearly more fat in the pancreas than people without it, as measured by MRI scans. The gap held across scan methods, regions, and study sizes. Body weight shaped the link, but the excess fat stayed even after weight, liver fat, and age were taken into account. The authors say this fat may be a mark of the disease and a possible target for care.
Catalog record
| CREATOR | Hyun Hee Sul, Saeed Ahmad, Pojsakorn Danpanichkul, Alessandro Mantovani, Matheus Souza, Maxim S. Petrov |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |