Characterisation of the axon initial segment and intrinsic excitability in the sub-acute phase post-ischaemic stroke

Emily S King, Jamie L Beros, Hakuei Fujiyama, Aidan Bindoff, John N J Reynolds, Alexander D Tang · 2026

Read Characterisation of the axon initial segment and intrinsic excitability in the sub-acute phase post-ischaemic stroke by Emily S King, Jamie L Beros, Hakuei Fujiyama, Aidan Bindoff, John N J Reynolds, Alexander D Tang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13190277.txt.

Description

King and co-authors study mouse brain cells after stroke in a 2026 paper. Stroke is a top cause of long-term disability, and odd changes in how brain cells fire may slow recovery. One suspect is the axon initial segment, the short zone where a nerve cell starts each signal.

The team caused a small stroke in the motor area of mice and marked two layers of nerve cells near the damage. Four weeks later they measured the start zone's shape and the cells' firing with fine electrodes. That time point falls in the sub-acute phase, when rehab often starts and the brain is most able to change. Their work tests whether early changes in the zone persist into that key window.

Catalog record

CREATOREmily S King, Jamie L Beros, Hakuei Fujiyama, Aidan Bindoff, John N J Reynolds, Alexander D Tang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE67 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13190277

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