EBV strain interacts with host HLA to drive nasopharyngeal carcinoma risk
Yanhong Chen, Jingtong Liang, Wanlin Zhang, Xinyu Zhang, Xinyi Zhang, Ching-Yuan Wang, Fei Yao, Shanshan Zhang, Xiang Zhou, Weimin Ye, Ruimei Feng, Yonglin Cai, Zhe Zhang, Mingfang Ji, Qian Cui, Xihong Lin, Jiesen Li, Jialei Xu, Qiuting Zhang, Qinyao Huang, Yingying Cheng, Yanran Luo, Xiaoping Ye, Q · 2026
Read EBV strain interacts with host HLA to drive nasopharyngeal carcinoma risk by Yanhong Chen, Jingtong Liang, Wanlin Zhang, Xinyu Zhang, Xinyi Zhang, Ching-Yuan Wang, Fei Yao, Shanshan Zhang, Xiang Zhou, Weimin Ye, Ruimei Feng, Yonglin Cai, Zhe Zhang, Mingfang Ji, Qian Cui, Xihong Lin, Jiesen Li, Jialei Xu, Qiuting Zhang, Qinyao Huang, Yingying Cheng, Yanran Luo, Xiaoping Ye, Q (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13190245.txt.
Description
Yanhong Chen and co-authors show that a virus strain and a host gene together drive throat cancer risk, in a 2026 study. The Epstein-Barr virus infects nearly all adults worldwide. Yet the cancer it links to clusters in southern China. The team analyzed host and virus genomes side by side. They found a pairing that sharply raises risk. One host gene form plus one virus variant form a dual-risk group.
That group covers about a fifth of the population. It accounts for nearly half of all cases. The virus variant makes a protein piece that binds the host gene's product. Immune cells raised against it can kill infected cells in tests. Carriers show lower virus levels in saliva and lower risk. The variant arose long ago from mixing of northern and southern virus lines. It then spread widely in the south. The work opens paths to targeted prevention.
Catalog record
| CREATOR | Yanhong Chen, Jingtong Liang, Wanlin Zhang, Xinyu Zhang, Xinyi Zhang, Ching-Yuan Wang, Fei Yao, Shanshan Zhang, Xiang Zhou, Weimin Ye, Ruimei Feng, Yonglin Cai, Zhe Zhang, Mingfang Ji, Qian Cui, Xihong Lin, Jiesen Li, Jialei Xu, Qiuting Zhang, Qinyao Huang, Yingying Cheng, Yanran Luo, Xiaoping Ye, Q |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 116 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |