Case Report: Preliminary evaluation of time-resolved imaging of contrast kinetics magnetic resonance imaging for assessing temporal enhancement patterns in small animal head and neck tumors
Sunghwa Hong, Soyeon Kim, Eunji Kim, Junghee Yoon, Jihye Choi · 2026
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Description
Time-resolved MR angiography follows contrast as it moves, revealing how a tumor's blood supply fills over time. The method is established for mapping vessels in animals, but its use for reading tumor enhancement patterns had not been described. The five authors test it on three client-owned animals: two dogs with intracranial meningiomas and one cat with a ceruminous gland adenocarcinoma, all imaged around radiation therapy.
In every case the time-resolved scans showed filling details that standard contrast MRI and triple-phase CT missed, such as delayed rim filling, inward-progressing enhancement, and patchy timing inside the tumor. Semi-quantitative measures, including time to enhance and slope values, matched those patterns. In two cases the scans flagged post-radiation change and non-enhancing defects before other methods did. The authors call this a feasibility report and ask for larger cohorts with tissue validation.
Catalog record
| CREATOR | Sunghwa Hong, Soyeon Kim, Eunji Kim, Junghee Yoon, Jihye Choi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |