Nicotinamide mononucleotide stimulates the activity of bursting slow-oscillation neurons in the supramammillary nucleus and enhances REM sleep
Youssouf Cissé, Cynthia S Brace, Virginia Hsu, Carla M Yuede, Nicholas Rensing, Michael Wong, Shin-ichiro Imai · 2026
Read Nicotinamide mononucleotide stimulates the activity of bursting slow-oscillation neurons in the supramammillary nucleus and enhances REM sleep by Youssouf Cissé, Cynthia S Brace, Virginia Hsu, Carla M Yuede, Nicholas Rensing, Michael Wong, Shin-ichiro Imai (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13187527.txt.
Description
SummaryNicotinamide mononucleotide (NMN) plays an important role in enhancing NAD+ levels and maintaining tissue functions in both mice and humans. Here, we show that NMN stimulates GABAergic neurons expressing Slc12a8, an NMN transporter, in the supramammillary (SuM) nucleus and enhances rapid eye movement (REM) sleep.
Catalog record
| CREATOR | Youssouf Cissé, Cynthia S Brace, Virginia Hsu, Carla M Yuede, Nicholas Rensing, Michael Wong, Shin-ichiro Imai |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 77 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |