Mendelian Randomization to Examine the Causal Effects of Cystatin on Ovarian Lesions
Tianqing Yan, Lin Guo, Renquan Lu · 2026
Read Mendelian Randomization to Examine the Causal Effects of Cystatin on Ovarian Lesions by Tianqing Yan, Lin Guo, Renquan Lu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13186221.txt.
Description
Tianqing Yan, Lin Guo, and Renquan Lu used genetics to test whether a family of proteins causes ovarian problems, in a 2026 study. The proteins, cystatins, rein in enzymes that cut other proteins, and earlier studies tied them to ovarian cancer and other lesions. Such links can mislead, since illness itself may shift protein levels.
The team used Mendelian randomization, a method that treats gene variants as a natural experiment. They tracked seven cystatin types against ovarian cysts, ovarian failure, twisting of the ovary, and several cancer subtypes. Data came from large gene banks in Finland and the United Kingdom. The design aims to separate true causes from mere fellow travelers.
Catalog record
| CREATOR | Tianqing Yan, Lin Guo, Renquan Lu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |