A Mouse in vivo Model Mimicking MASH-Related HCC Pathogenesis
Tianxiao Zheng, Zhi Pei, Enze Cui, Luyuan Zhu, Juan Du, Changquan Ling · 2026
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Description
Tianxiao Zheng leads a team that builds a mouse model of MASH linked liver cancer. Their study from twenty twenty-six deals with hepatocellular carcinoma. The cancer type draws growing attention in liver research.
Older models miss key traits of the human disease. They also take too long to run their course. The new model pairs a special diet with gene drivers. The diet lacks choline and is high in fat. Two cancer genes were delivered into the liver. Tissue checks tracked the disease stages over time. Gene profiles were matched to human cases.
Catalog record
| CREATOR | Tianxiao Zheng, Zhi Pei, Enze Cui, Luyuan Zhu, Juan Du, Changquan Ling |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |