Advances and Challenges in 3D Bioprinting of Cartilage Organoids: From Material Innovation to Functional Regeneration

Zhengcai Han, Jiwei Huang, Xiaoming Qiu · 2026

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Description

Zhengcai Han, Jiwei Huang, and Xiaoming Qiu review progress in 3D bioprinting of cartilage organoids, in work published in 2026. Cartilage has no blood vessels or nerves, so it heals very poorly after injury. Organoids are small lab-grown constructs that copy key features of real cartilage, and printing can place their cells and materials with fine control.

The review first covers bioink design, from natural and synthetic gels to reinforced mixes and smart materials that respond to signals. Good inks must copy the native matrix while still printing cleanly. It then turns to printing methods and the move from printed shapes to working tissue. Uses include personal therapy, disease models, and regenerative medicine. The authors weigh what still blocks clinical use.

Catalog record

CREATORZhengcai Han, Jiwei Huang, Xiaoming Qiu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE74 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13185957

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