Reduced thalamic glutathione in migraine: a MEGA-PRESS spectroscopy study

Hongying Huang, Jiayin Miao, Yinji Piao, Zhaodong Lin, Yuqin Lin, Rui Wang, Zhongruowen Ren, Guangsong Wang, Dafa Shi, Gen Yan, Yongmin Chang, Renhua Wu · 2026

Read Reduced thalamic glutathione in migraine: a MEGA-PRESS spectroscopy study by Hongying Huang, Jiayin Miao, Yinji Piao, Zhaodong Lin, Yuqin Lin, Rui Wang, Zhongruowen Ren, Guangsong Wang, Dafa Shi, Gen Yan, Yongmin Chang, Renhua Wu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13185357.txt.

Description

Hongying Huang and ten colleagues measure a protective brain chemical in people with migraine and tension headache, in a 2026 study. The two headache types can look alike, yet no lab test separates them.

Seventy-six participants, healthy volunteers plus both patient groups, had the chemical glutathione read in the thalamus by a tuned spectroscopy method. Migraine patients showed clearly lower levels than both other groups, on the left side especially. Tension headache patients matched the healthy group. The drop held for men and women alike. A simple cutoff on left thalamus values separated migraine from the rest with good accuracy. The authors propose the measure as a candidate diagnostic marker.

Catalog record

CREATORHongying Huang, Jiayin Miao, Yinji Piao, Zhaodong Lin, Yuqin Lin, Rui Wang, Zhongruowen Ren, Guangsong Wang, Dafa Shi, Gen Yan, Yongmin Chang, Renhua Wu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE48 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13185357

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