Evaluation and management of worsening virilization in a postmenopausal woman diagnosed with PCOS
Matthew F Osborne, William B Horton, Arthur J Pesch, Richard J Santen · 2026
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Description
Matthew Osborne and three co-authors walk through a 2026 case where a common diagnosis hid a rare tumor. A postmenopausal woman carried a label of polycystic ovary syndrome, a common cause of male hormone excess. Her male traits kept worsening after menopause, a pattern that does not fit the common story.
A careful history raised the flag. Tests found a steroid cell tumor of the ovary, a growth so rare it makes up a sliver of such cases. Such tumors switch on fast and hard, unlike the slow course of the common syndrome. The authors lay out how to sort look-alike causes when the story turns odd.
Catalog record
| CREATOR | Matthew F Osborne, William B Horton, Arthur J Pesch, Richard J Santen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |