From complexity to clarity: aging bone marrow niche in bone and blood regeneration and malignancy

Nainita Roy, Hanyu Liu, Allison L Horenberg, Arvind P Pathak, Junyu Chen, Saravana K Ramasamy, Martine Cohen-Solal, Aline Bozec, Warren L Grayson, Anjali P Kusumbe · 2026

Read From complexity to clarity: aging bone marrow niche in bone and blood regeneration and malignancy by Nainita Roy, Hanyu Liu, Allison L Horenberg, Arvind P Pathak, Junyu Chen, Saravana K Ramasamy, Martine Cohen-Solal, Aline Bozec, Warren L Grayson, Anjali P Kusumbe (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13184274.txt.

Description

Nainita Roy and a team of co-authors reviewed how the bone marrow space ages. Their review, from twenty twenty-six, looks at the niche that holds blood stem cells. This space keeps stem cells in balance, guides their split into blood lines, and guards body defense. It also helps build bone and keep the skeleton sound. Long seen as still, it is now known to shift with need and stress.

Aging reshapes this niche in deep ways, and work in both blood and support cells falls off. New imaging and single cell tools show a rich mix of cell types and states. Readers get a clear view of how age harms blood and bone repair, and where cancer risk grows.

Catalog record

CREATORNainita Roy, Hanyu Liu, Allison L Horenberg, Arvind P Pathak, Junyu Chen, Saravana K Ramasamy, Martine Cohen-Solal, Aline Bozec, Warren L Grayson, Anjali P Kusumbe
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE82 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13184274

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