Type B Aortic Dissection Following Abdominal Aortic Aneurysm Repair in Loeys–Dietz Syndrome: A Novel TGFBR1 Variant
Yuchong Zhang, Shouji Qiu, Chengkai Hu, Li Zhang, Wei Guo, Weiguo Fu, Lixin Wang · 2026
Read Type B Aortic Dissection Following Abdominal Aortic Aneurysm Repair in Loeys–Dietz Syndrome: A Novel TGFBR1 Variant by Yuchong Zhang, Shouji Qiu, Chengkai Hu, Li Zhang, Wei Guo, Weiguo Fu, Lixin Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13184162.txt.
Description
Yuchong Zhang and co-authors report a new gene variant in a woman with Loeys-Dietz syndrome, a disease that weakens the aorta. She came in at forty-four with a fast-growing bulge in her belly aorta that threatened to burst. Surgeons rebuilt the vessel in open surgery. Their 2026 report follows what happened next and what gene tests found.
Two months later a tear split a lower stretch of her aorta, forcing a second open operation. Gene reads found a fresh variant in TGFBR1, a gene long tied to the syndrome, sitting in a key working part of its protein. Modeling and tissue tests showed the variant over-fires a growth signal. The authors say symptoms and fast growth may justify surgery before size rules say so.
Catalog record
| CREATOR | Yuchong Zhang, Shouji Qiu, Chengkai Hu, Li Zhang, Wei Guo, Weiguo Fu, Lixin Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |