PPARα deficiency causes skin dysbiosis and triggers innate immunity in keratinocytes

Stefan Blunder, Deborah Minzaghi, Petra Pavel, Michael Berktold, Martin Hermann, Christian Ploner, Cristina Schöpf, Florentine Marx, Sandrine Dubrac · 2026

Read PPARα deficiency causes skin dysbiosis and triggers innate immunity in keratinocytes by Stefan Blunder, Deborah Minzaghi, Petra Pavel, Michael Berktold, Martin Hermann, Christian Ploner, Cristina Schöpf, Florentine Marx, Sandrine Dubrac (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13183956.txt.

Description

Peroxisome proliferator-activated receptor-α (PPARα) is a transcription factor expressed in the skin, where its physiological role remains largely unknown. In this work, we found decreased bacterial density and dysbiosis associated with reduced amounts of Staphylococcus in the skin of PPARα-deficient mice compared to littermate controls.

Catalog record

CREATORStefan Blunder, Deborah Minzaghi, Petra Pavel, Michael Berktold, Martin Hermann, Christian Ploner, Cristina Schöpf, Florentine Marx, Sandrine Dubrac
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13183956

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