The Role of N6‐Methyladenosine Modification in Health and Disease

Linghuan Li, Yuanhai Sun, Wanfang Zheng, Lingqin Li, Yaqian Feng, Minyou Qi, Hanbing Li · 2026

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Description

Linghuan Li and co-authors review the most common chemical tag on RNA in a 2026 paper. The tag, called m6A, is added to messenger RNA inside cells and steers how those messages are spliced, shipped, preserved, and read into protein.

When the tag's writers, erasers, and readers fall out of balance, diseases from metabolic disorders to cancer can follow. The review maps that double life, guardian of normal cell order in health and driver of trouble in disease. A special section follows the tag into the mitochondria, the cell's power plants. The authors close with the newest mapping tools and drugs that target the tag system, a fast-moving frontier for treatment design.

Catalog record

CREATORLinghuan Li, Yuanhai Sun, Wanfang Zheng, Lingqin Li, Yaqian Feng, Minyou Qi, Hanbing Li
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE172 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13183813

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