Successful Treatment of Evans Syndrome Onset With Zanubrutinib in Combination With Romiplostim During Venetoclax Treatment in a Patient With Chronic Lymphocytic Leukemia: A Case Report

Vanessa Innao, Alessia Paola Maria Barbagallo, Oriana Bianco, Valerio Leotta, Ugo Consoli · 2026

Read Successful Treatment of Evans Syndrome Onset With Zanubrutinib in Combination With Romiplostim During Venetoclax Treatment in a Patient With Chronic Lymphocytic Leukemia: A Case Report by Vanessa Innao, Alessia Paola Maria Barbagallo, Oriana Bianco, Valerio Leotta, Ugo Consoli (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13183772.txt.

Description

Vanessa Innao and co-authors present a 2026 case report on a hard clash of treatments. A blood cancer drug seemed to trigger a severe immune attack on the patient's own blood cells.

The patient, a man aged 75 with chronic lymphocytic leukemia, developed Evans syndrome while starting the drug venetoclax. His platelet count fell to near zero, and steroids and other standard drugs failed to help. Doctors then paired two other drugs: one that boosts platelet growth and one that blocks a key enzyme in the cancer cells. Within four weeks his platelet count fully recovered and stayed stable. The case offers a rescue path when standard care fails in this rare setting.

Catalog record

CREATORVanessa Innao, Alessia Paola Maria Barbagallo, Oriana Bianco, Valerio Leotta, Ugo Consoli
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE11 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13183772

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