Incidence of Second Malignancies Among Children Treated for Cancer With Radiotherapy in Egypt

Charlotte L Sackett, Mohamed S Zaghloul, Ahmed Aldesouky, Alaa Elhaddad, Li Zhang, Chloe A Teasdale, Amr S Soliman · 2026

Read Incidence of Second Malignancies Among Children Treated for Cancer With Radiotherapy in Egypt by Charlotte L Sackett, Mohamed S Zaghloul, Ahmed Aldesouky, Alaa Elhaddad, Li Zhang, Chloe A Teasdale, Amr S Soliman (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13183492.txt.

Description

Charlotte Sackett and co-authors measured in 2026 how often Egyptian children treated with radiotherapy for cancer later developed a second cancer. They followed 3,132 young patients treated in Cairo from 2009 to 2015, tracking them through 2021. Second cancers are a feared late effect of the very treatments that save children.

Twenty-three patients developed a second malignancy, a cumulative incidence of about 1.85 percent over eleven years. That matches rates in wealthy countries. About a third of the new cancers arose inside the earlier radiation field. Those in-field cases took longer to appear, about eight years versus four. The authors stress that strong long-term follow-up is essential for childhood cancer survivors in Egypt and similar settings.

Catalog record

CREATORCharlotte L Sackett, Mohamed S Zaghloul, Ahmed Aldesouky, Alaa Elhaddad, Li Zhang, Chloe A Teasdale, Amr S Soliman
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE30 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13183492

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