Successful treatment of anti-LGI1-associated autoimmune encephalitis with efgartigimod: A case report and literature review
Rui Gao, Yan Hong, Guanen Zhou · 2026
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Description
Rui Gao, Yan Hong, and Guanen Zhou report a 2026 case of a brain illness tied to the immune system. A 64-year-old woman lost short-term memory and had shaky limbs. Scans showed swelling in one part of her brain, and tests found a harmful antibody in her blood and spinal fluid. Care with steroids and seizure drugs did not help her.
The team then gave a drug called efgartigimod once a week for three weeks. The drug speeds the breakdown of the harmful antibody by blocking its reuse in the body. Her shaking stopped, her memory got better, and her antibody level fell. The authors add a review of past cases and say dose and long-term safety still need study.
Catalog record
| CREATOR | Rui Gao, Yan Hong, Guanen Zhou |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |