Immune cell contributions to sarcopenia: Evidence from genetic analyses
Yuanjie Duan, Juan Liu, Shiyu Lin, Xi Li, Dan Luo, Lemei Zhu · 2026
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Description
Yuanjie Duan and co-authors use gene data to study muscle loss in a 2026 paper. Sarcopenia, the loss of muscle and strength with age, may be shaped by immune cells. Past work hints at a link but cannot show which side causes the other.
The team used a method that reads cause from gene variants tied to immune traits. Data covered hundreds of immune cell traits and large gene studies of grip, muscle mass, and walking pace. Some traits on defense cells went with lower muscle mass and slower pace. Other traits on T and B cells looked protective instead. Tests in the reverse direction found no strong effect. The authors point to defense cells as a target for future work.
Catalog record
| CREATOR | Yuanjie Duan, Juan Liu, Shiyu Lin, Xi Li, Dan Luo, Lemei Zhu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 18 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |